English+GermanWikipedia - /page/entry.mu

Micron Document

<!DOCTYPE html>

<title>CREB-Binding-Protein</title>

</head>

<h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">CREB-Binding-Protein</span></h1>

</header>

</div>

<th colspan="3" style="background:#90EE90; color:#202122;">CREB-Binding-Protein

</th></tr>

<tr>

<p>Vorhandene Strukturdaten: s. UniProt

</p>

</td></tr>

<tr>

<th colspan="3" style="background:#90EE90; color:#202122;;">Eigenschaften des menschlichen Proteins

</th></tr>

<tr>

<td><a href="Molare_Masse" title="Molare Masse">Masse</a>/Länge <a href="Prim%C3%A4rstruktur" title="Primärstruktur">Primärstruktur</a>

</td>

<td colspan="2" style="text-align:center;">2442 Aminosäuren

</td></tr>

<tr>

<th colspan="3" style="background:#90EE90; color:#202122;">Bezeichner

</th></tr>

<tr>

</td>

<td colspan="2" class="" style="text-align:center;"><i><a rel="nofollow" class="external text" href="https://www.genenames.org/tools/search/#!/all?query=2348">CREBBP</a></i>

</td></tr>

<tr>

<td>Externe IDs

</td>

<li><a href="UniProt" title="UniProt">UniProt</a> <a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprotkb/Q92793">Q92793</a></li></ul>

</td></tr>

<tr>

<th colspan="3" style="background:#90EE90; color:#202122;">Enzymklassifikation

</th></tr>

<tr>

<td><a href="EC-Nummer" title="EC-Nummer">EC, Kategorie</a>

</td>

<td colspan="2" class="" style="text-align:center;"><a rel="nofollow" class="external text" href="https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.48">2.3.1.48</a>, <a href="Acetyltransferase" title="Acetyltransferase">Acetyltransferase</a>

</td></tr>

<tr>

<td>Reaktionsart

</td>

<td colspan="2" style="text-align:center;">Übertragung einer Acetylgruppe

</td></tr>

<tr>

<td>Substrat

</td>

<td colspan="2" style="text-align:center;">Histon + Acetyl-CoA

</td></tr>

<tr>

<td>Produkte

</td>

<td colspan="2" style="text-align:center;">Acetylhiston + CoA

</td></tr>

<tr>

<th colspan="3" style="background:#90EE90; color:#202122;">Vorkommen

</th></tr>

<tr>

<td style="background:#C3FDB8; color:#202122;">Homologie-Familie

</td>

<td colspan="2" style="text-align:center;"><a rel="nofollow" class="external text" href="http://hogenom.univ-lyon1.fr/query_sequence?seq=Q92793">CREBBP</a>

</td></tr>

<tr>

<td style="background:#C3FDB8; color:#202122;">Übergeordnetes <a href="Taxon" title="Taxon">Taxon</a>

</td>

<td colspan="2" style="text-align:center;"><a href="Euteleostomi" title="Euteleostomi">Euteleostomi</a>

</td></tr>

</tbody></table><p><span class="editoronly" style="display:none;"></span>

</p><p>Das <b>C</b>REB-<b>B</b>inding <b>P</b>rotein (CREB-Bindeprotein), kurz <b>CBP</b>, ist ein Coaktivator der <a href="Transkription_(Biologie)" title="Transkription (Biologie)">Transkription</a>.

</p><p>CBP stellt eine Verbindung zwischen dem <a href="Transkriptionsfaktor" title="Transkriptionsfaktor">Transkriptionsfaktor</a> <a href="CREB" class="mw-redirect" title="CREB">CREB</a> und dem <a href="Transkriptionsstartpunkt" title="Transkriptionsstartpunkt">Transkriptionsstartpunkt</a> her, indem es als Histon-Acetyltransferase (HAT, <a href="EC-Nummer" title="EC-Nummer">EC</a> <a rel="nofollow" class="external text" href="https://enzyme.expasy.org/EC/2.3.1.48">2.3.1.48</a>) die <a href="Chromatin" title="Chromatin">Chromatin</a>-Struktur verändert, die dadurch aufgelockert wird. CBP zeigt Homologien zum ebenfalls als HAT wirkenden Protein p300. CBP und p300 acetylieren bevorzugt die <a href="Histon" title="Histon">Histone</a> H3 und H4.

</p><p>CBP ist ein Coaktivator allgemeiner Natur und wechselwirkt z. B. auch mit <a href="Transkriptionsfaktor" title="Transkriptionsfaktor">Transkriptionsfaktoren</a>.

</p>

<div class="mw-heading mw-heading2"><h2 id="Struktur">Struktur</h2></div>

<div class="mw-heading mw-heading2"><h2 id="Klinische_Bedeutung">Klinische Bedeutung</h2></div>

<p>Mutationen in diesem <a href="Gen" title="Gen">Gen</a> sind für das <a href="Rubinstein-Taybi-Syndrom" title="Rubinstein-Taybi-Syndrom">Rubinstein-Taybi-Syndrom</a> (RTS) verantwortlich.<sup id="cite_ref-pmid7630403_1-0" class="reference"><a href="#cite_note-pmid7630403-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup>

</p>

<div class="mw-heading mw-heading2"><h2 id="Siehe_auch">Siehe auch</h2></div>

<ul><li><a href="Histonmodifikation" title="Histonmodifikation">Histonmodifikation</a></li></ul>

<div class="mw-heading mw-heading2"><h2 id="Einzelnachweise">Einzelnachweise</h2></div>

<li id="cite_note-pmid7630403-1"><span class="mw-cite-backlink"><a href="#cite_ref-pmid7630403_1-0">↑</a></span> <span class="reference-text">Petrij F, Giles RH, Dauwerse HG, Saris JJ, Hennekam RC, Masuno M, Tommerup N, van Ommen GJ, Goodman RH, Peters DJ: <cite style="font-style:italic">Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP</cite>. In: <cite style="font-style:italic"><a href="Nature" title="Nature">Nature</a></cite>. 376. Jahrgang, <span style="white-space:nowrap">Nr.<span style="display:inline-block;width:.2em"> </span>6538</span>, Juli 1995, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>348–51</span>, <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.1038/376348a0">10.1038/376348a0</a></span>, <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/7630403?dopt=Abstract">PMID 7630403</a>, <a href="Bibcode" title="Bibcode">bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/1995Natur.376..348P">1995Natur.376..348P</a>.<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rfr_id=info:sid/de.wikipedia.org:CREB-Binding-Protein&rft.atitle=Rubinstein-Taybi+syndrome+caused+by+mutations+in+the+transcriptional+co-activator+CBP&rft.au=Petrij+F%2C+Giles+RH%2C+Dauwerse+HG%2C+...&rft.date=1995-07&rft.doi=10.1038%2F376348a0&rft.genre=journal&rft.issue=6538&rft.jtitle=Nature&rft.pages=348-51&rft.pmid=7630403&rft.volume=376.+Jahrgang" style="display:none"> </span></span>

</li>

</ol>

<div class="mw-heading mw-heading2"><h2 id="Literatur">Literatur</h2></div>

<ul><li>Rolf Knippers: <i>Molekulare Genetik</i>. 9. Auflage. Georg Thieme Verlag, 2006, ISBN 3-13-477009-1</li>

<li>Goldman PS, Tran VK, Goodman RH: <cite style="font-style:italic">The multifunctional role of the co-activator CBP in transcriptional regulation.</cite> In: <cite style="font-style:italic">Recent Prog. Horm. Res.</cite> 52. Jahrgang, 1997, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>103–19; discussion 119–20</span>, <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/9238849?dopt=Abstract">PMID 9238849</a>.<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rfr_id=info:sid/de.wikipedia.org:CREB-Binding-Protein&rft.atitle=The+multifunctional+role+of+the+co-activator+CBP+in+transcriptional+regulation.&rft.au=Goldman+PS%2C+Tran+VK%2C+Goodman+RH&rft.btitle=Recent+Prog.+Horm.+Res.&rft.date=1997&rft.genre=book&rft.pages=103-19%3B+discussion+119-20&rft.pmid=9238849&rft.volume=52.+Jahrgang" style="display:none"> </span></li>

<li>Marcello A, Zoppé M, Giacca M: <cite style="font-style:italic">Multiple modes of transcriptional regulation by the HIV-1 Tat transactivator.</cite> In: <cite style="font-style:italic">IUBMB Life</cite>. 51. Jahrgang, <span style="white-space:nowrap">Nr.<span style="display:inline-block;width:.2em"> </span>3</span>, 2002, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>175–81</span>, <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.1080/152165401753544241">10.1080/152165401753544241</a></span>, <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/11547919?dopt=Abstract">PMID 11547919</a>.<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rfr_id=info:sid/de.wikipedia.org:CREB-Binding-Protein&rft.atitle=Multiple+modes+of+transcriptional+regulation+by+the+HIV-1+Tat+transactivator.&rft.au=Marcello+A%2C+Zopp%C3%A9+M%2C+Giacca+M&rft.date=2002&rft.doi=10.1080%2F152165401753544241&rft.genre=journal&rft.issue=3&rft.jtitle=IUBMB+Life&rft.pages=175-81&rft.pmid=11547919&rft.volume=51.+Jahrgang" style="display:none"> </span></li>

<li>Matt T: <cite style="font-style:italic">Transcriptional control of the inflammatory response: a role for the CREB-binding protein (CBP).</cite> In: <cite style="font-style:italic">Acta Med. Austriaca</cite>. 29. Jahrgang, <span style="white-space:nowrap">Nr.<span style="display:inline-block;width:.2em"> </span>3</span>, 2002, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>77–9</span>, <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.1046/j.1563-2571.2002.02010.x">10.1046/j.1563-2571.2002.02010.x</a></span>, <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/12168567?dopt=Abstract">PMID 12168567</a>.<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rfr_id=info:sid/de.wikipedia.org:CREB-Binding-Protein&rft.atitle=Transcriptional+control+of+the+inflammatory+response%3A+a+role+for+the+CREB-binding+protein+%28CBP%29.&rft.au=Matt+T&rft.date=2002&rft.doi=10.1046%2Fj.1563-2571.2002.02010.x&rft.genre=journal&rft.issue=3&rft.jtitle=Acta+Med.+Austriaca&rft.pages=77-9&rft.pmid=12168567&rft.volume=29.+Jahrgang" style="display:none"> </span></li>

<li>Combes R, Balls M, Bansil L, <i>et al.</i>: <cite style="font-style:italic">An assessment of progress in the use of alternatives in toxicity testing since the publication of the report of the second FRAME Toxicity Committee (1991).</cite> In: <cite style="font-style:italic">Alternatives to laboratory animals : ATLA</cite>. 30. Jahrgang, <span style="white-space:nowrap">Nr.<span style="display:inline-block;width:.2em"> </span>4</span>, 2002, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>365–406</span>, <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/12234245?dopt=Abstract">PMID 12234245</a>.<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rfr_id=info:sid/de.wikipedia.org:CREB-Binding-Protein&rft.atitle=An+assessment+of+progress+in+the+use+of+alternatives+in+toxicity+testing+since+the+publication+of+the+report+of+the+second+FRAME+Toxicity+Committee+%281991%29.&rft.au=Combes+R%2C+Balls+M%2C+Bansil+L%2C+...&rft.date=2002&rft.genre=journal&rft.issue=4&rft.jtitle=Alternatives+to+laboratory+animals+%3A+ATLA&rft.pages=365-406&rft.pmid=12234245&rft.volume=30.+Jahrgang" style="display:none"> </span></li>

<li>Minghetti L, Visentin S, Patrizio M, <i>et al.</i>: <cite style="font-style:italic">Multiple actions of the human immunodeficiency virus type-1 Tat protein on microglial cell functions.</cite> In: <cite style="font-style:italic">Neurochem. Res.</cite> 29. Jahrgang, <span style="white-space:nowrap">Nr.<span style="display:inline-block;width:.2em"> </span>5</span>, 2004, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>965–78</span>, <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.1023/B%3ANERE.0000021241.90133.89">10.1023/B:NERE.0000021241.90133.89</a></span>, <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/15139295?dopt=Abstract">PMID 15139295</a>.<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rfr_id=info:sid/de.wikipedia.org:CREB-Binding-Protein&rft.atitle=Multiple+actions+of+the+human+immunodeficiency+virus+type-1+Tat+protein+on+microglial+cell+functions.&rft.au=Minghetti+L%2C+Visentin+S%2C+Patrizio+M%2C+...&rft.date=2004&rft.doi=10.1023%2FB%3ANERE.0000021241.90133.89&rft.genre=journal&rft.issue=5&rft.jtitle=Neurochem.+Res.&rft.pages=965-78&rft.pmid=15139295&rft.volume=29.+Jahrgang" style="display:none"> </span></li>

<li>Kino T, Pavlakis GN: <cite style="font-style:italic">Partner molecules of accessory protein Vpr of the human immunodeficiency virus type 1.</cite> In: <cite style="font-style:italic">DNA Cell Biol.</cite> 23. Jahrgang, <span style="white-space:nowrap">Nr.<span style="display:inline-block;width:.2em"> </span>4</span>, 2004, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>193–205</span>, <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.1089/104454904773819789">10.1089/104454904773819789</a></span>, <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/15142377?dopt=Abstract">PMID 15142377</a>.<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rfr_id=info:sid/de.wikipedia.org:CREB-Binding-Protein&rft.atitle=Partner+molecules+of+accessory+protein+Vpr+of+the+human+immunodeficiency+virus+type+1.&rft.au=Kino+T%2C+Pavlakis+GN&rft.date=2004&rft.doi=10.1089%2F104454904773819789&rft.genre=journal&rft.issue=4&rft.jtitle=DNA+Cell+Biol.&rft.pages=193-205&rft.pmid=15142377&rft.volume=23.+Jahrgang" style="display:none"> </span></li>

<li>Greene WC, Chen LF: <cite style="font-style:italic">Regulation of NF-kappaB action by reversible acetylation.</cite> In: <cite style="font-style:italic">Novartis Found. Symp.</cite> 259. Jahrgang, 2004, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>208–17; discussion 218–25</span>, <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.1002/0470862637.ch15">10.1002/0470862637.ch15</a></span>, <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/15171256?dopt=Abstract">PMID 15171256</a>.<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rfr_id=info:sid/de.wikipedia.org:CREB-Binding-Protein&rft.atitle=Regulation+of+NF-kappaB+action+by+reversible+acetylation.&rft.au=Greene+WC%2C+Chen+LF&rft.btitle=Novartis+Found.+Symp.&rft.date=2004&rft.doi=10.1002%2F0470862637.ch15&rft.genre=book&rft.pages=208-17%3B+discussion+218-25&rft.pmid=15171256&rft.volume=259.+Jahrgang" style="display:none"> </span></li>

<li>Liou LY, Herrmann CH, Rice AP: <cite style="font-style:italic">HIV-1 infection and regulation of Tat function in macrophages.</cite> In: <cite style="font-style:italic">Int. J. Biochem. Cell Biol.</cite> 36. Jahrgang, <span style="white-space:nowrap">Nr.<span style="display:inline-block;width:.2em"> </span>9</span>, 2005, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>1767–75</span>, <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.1016/j.biocel.2004.02.018">10.1016/j.biocel.2004.02.018</a></span>, <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/15183343?dopt=Abstract">PMID 15183343</a>.<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rfr_id=info:sid/de.wikipedia.org:CREB-Binding-Protein&rft.atitle=HIV-1+infection+and+regulation+of+Tat+function+in+macrophages.&rft.au=Liou+LY%2C+Herrmann+CH%2C+Rice+AP&rft.date=2005&rft.doi=10.1016%2Fj.biocel.2004.02.018&rft.genre=journal&rft.issue=9&rft.jtitle=Int.+J.+Biochem.+Cell+Biol.&rft.pages=1767-75&rft.pmid=15183343&rft.volume=36.+Jahrgang" style="display:none"> </span></li>

<li>Pugliese A, Vidotto V, Beltramo T, <i>et al.</i>: <cite style="font-style:italic">A review of HIV-1 Tat protein biological effects.</cite> In: <cite style="font-style:italic">Cell Biochem. Funct.</cite> 23. Jahrgang, <span style="white-space:nowrap">Nr.<span style="display:inline-block;width:.2em"> </span>4</span>, 2005, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>223–7</span>, <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.1002/cbf.1147">10.1002/cbf.1147</a></span>, <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/15473004?dopt=Abstract">PMID 15473004</a>.<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rfr_id=info:sid/de.wikipedia.org:CREB-Binding-Protein&rft.atitle=A+review+of+HIV-1+Tat+protein+biological+effects.&rft.au=Pugliese+A%2C+Vidotto+V%2C+Beltramo+T%2C+...&rft.date=2005&rft.doi=10.1002%2Fcbf.1147&rft.genre=journal&rft.issue=4&rft.jtitle=Cell+Biochem.+Funct.&rft.pages=223-7&rft.pmid=15473004&rft.volume=23.+Jahrgang" style="display:none"> </span></li>

<li>Bannwarth S, Gatignol A: <cite style="font-style:italic">HIV-1 TAR RNA: the target of molecular interactions between the virus and its host.</cite> In: <cite style="font-style:italic">Curr. HIV Res.</cite> 3. Jahrgang, <span style="white-space:nowrap">Nr.<span style="display:inline-block;width:.2em"> </span>1</span>, 2005, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>61–71</span>, <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.2174/1570162052772924">10.2174/1570162052772924</a></span>, <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/15638724?dopt=Abstract">PMID 15638724</a>.<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rfr_id=info:sid/de.wikipedia.org:CREB-Binding-Protein&rft.atitle=HIV-1+TAR+RNA%3A+the+target+of+molecular+interactions+between+the+virus+and+its+host.&rft.au=Bannwarth+S%2C+Gatignol+A&rft.date=2005&rft.doi=10.2174%2F1570162052772924&rft.genre=journal&rft.issue=1&rft.jtitle=Curr.+HIV+Res.&rft.pages=61-71&rft.pmid=15638724&rft.volume=3.+Jahrgang" style="display:none"> </span></li>

<li>Le Rouzic E, Benichou S: <cite style="font-style:italic">The Vpr protein from HIV-1: distinct roles along the viral life cycle.</cite> In: <cite style="font-style:italic">Retrovirology</cite>. 2. Jahrgang, 2006, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>11</span>, <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.1186/1742-4690-2-11">10.1186/1742-4690-2-11</a></span>, <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/15725353?dopt=Abstract">PMID 15725353</a>, <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC554975/">PMC 554975</a> (freier Volltext).<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rfr_id=info:sid/de.wikipedia.org:CREB-Binding-Protein&rft.atitle=The+Vpr+protein+from+HIV-1%3A+distinct+roles+along+the+viral+life+cycle.&rft.au=Le+Rouzic+E%2C+Benichou+S&rft.btitle=Retrovirology&rft.date=2006&rft.doi=10.1186%2F1742-4690-2-11&rft.genre=book&rft.pages=11&rft.pmc=554975&rft.pmid=15725353&rft.volume=2.+Jahrgang" style="display:none"> </span></li>

<li>Gibellini D, Vitone F, Schiavone P, Re MC: <cite style="font-style:italic">HIV-1 tat protein and cell proliferation and survival: a brief review.</cite> In: <cite style="font-style:italic">New Microbiol.</cite> 28. Jahrgang, <span style="white-space:nowrap">Nr.<span style="display:inline-block;width:.2em"> </span>2</span>, 2005, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>95–109</span>, <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/16035254?dopt=Abstract">PMID 16035254</a>.<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rfr_id=info:sid/de.wikipedia.org:CREB-Binding-Protein&rft.atitle=HIV-1+tat+protein+and+cell+proliferation+and+survival%3A+a+brief+review.&rft.au=Gibellini+D%2C+Vitone+F%2C+Schiavone+P%2C+...&rft.date=2005&rft.genre=journal&rft.issue=2&rft.jtitle=New+Microbiol.&rft.pages=95-109&rft.pmid=16035254&rft.volume=28.+Jahrgang" style="display:none"> </span></li>

<li>Hetzer C, Dormeyer W, Schnölzer M, Ott M: <cite style="font-style:italic">Decoding Tat: the biology of HIV Tat posttranslational modifications.</cite> In: <cite style="font-style:italic">Microbes Infect.</cite> 7. Jahrgang, <span style="white-space:nowrap">Nr.<span style="display:inline-block;width:.2em"> </span>13</span>, 2006, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>1364–9</span>, <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.1016/j.micinf.2005.06.003">10.1016/j.micinf.2005.06.003</a></span>, <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/16046164?dopt=Abstract">PMID 16046164</a>.<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rfr_id=info:sid/de.wikipedia.org:CREB-Binding-Protein&rft.atitle=Decoding+Tat%3A+the+biology+of+HIV+Tat+posttranslational+modifications.&rft.au=Hetzer+C%2C+Dormeyer+W%2C+Schn%C3%B6lzer+M%2C+...&rft.date=2006&rft.doi=10.1016%2Fj.micinf.2005.06.003&rft.genre=journal&rft.issue=13&rft.jtitle=Microbes+Infect.&rft.pages=1364-9&rft.pmid=16046164&rft.volume=7.+Jahrgang" style="display:none"> </span></li>

<li>Peruzzi F: <cite style="font-style:italic">The multiple functions of HIV-1 Tat: proliferation versus apoptosis.</cite> In: <cite style="font-style:italic">Front. Biosci.</cite> 11. Jahrgang, 2006, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>708–17</span>, <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.2741/1829">10.2741/1829</a></span>, <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/16146763?dopt=Abstract">PMID 16146763</a>.<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rfr_id=info:sid/de.wikipedia.org:CREB-Binding-Protein&rft.atitle=The+multiple+functions+of+HIV-1+Tat%3A+proliferation+versus+apoptosis.&rft.au=Peruzzi+F&rft.btitle=Front.+Biosci.&rft.date=2006&rft.doi=10.2741%2F1829&rft.genre=book&rft.pages=708-17&rft.pmid=16146763&rft.volume=11.+Jahrgang" style="display:none"> </span></li></ul></div><div><div class="zim-footer">

Dieser Artikel wurde von <a class="external text" title="Zuletzt bearbeitet am 2016-06-05" href="https://de.wikipedia.org/wiki/?title=CREB-Binding-Protein&oldid=155001214">Wikipedia</a> herausgegeben. Der Text ist unter <a class="external text" href="https://creativecommons.org/licenses/by-sa/4.0/deed.de">Creative Commons Attribution-Share Alike 4.0</a> verfügbar, sofern nicht anders angegeben. Für die Mediendateien können zusätzliche Bedingungen gelten.

</div>

</div></div>

</div>

</main>

</div>

</body></html>